Oclacitinib Maleate Tablets

Active ingredient

Oclacitinib Maleate

Appearance

This product is a light brown or brown, cross-scored tablet.

Dosage and Administration

Calculated as oclacitinib. Oral administration: For dogs, 0.4 ? 0.6 mg per 1 kg of body weight, twice a day for 14 consecutive days, and then once a day for maintenance therapy.

Oclacitinib is a synthetic intracellular non-receptor tyrosine kinase Janus kinase, JAK for short inhibitor. It inhibits the function of a variety of pruritogenic cytokines and pro-inflammatory cytokines, as well as cytokines involved in allergy that are dependent on JAK1 or JAK3 enzyme activity. It has little effect on cytokines involved in hematopoiesis that are dependent on JAK2.