HPMC E3

KimaCell®HPMC E3 is pharmaceutical excipient grade hydroxypropyl methyl cellulose, hypromellose, is a cellulose-based polymer for film coating, pellet granulation, and hard capsule manufacturing. Hydroxypropylmethylcellulose HPMC is a semi-synthetic, inert, viscoelastic polymer used as eye drops, and as a tablet coating, binder, and controlled release ingredient in oral medicines, present in many of commercial products.



Specification of HPMC E3



HPMC E3  9004 65 3 

Hydroxypropyl Methyl Cellulose HPMC

Physical Analysis of HPMC E3

Appearance White to slightly off-white fibrous or granular powder.

Identification A to E Conform

Solution appearance Conform

Methoxy 28.0-30.0%

Hydroxypropoxy 7.0-12.0%

Loss on drying 5.0% Max

Residue on ignition 1.5% Max

pH 5.0-8.0

Apparent viscosity 2.4-3.6cps

Particle size Min. 98% pass through 100 mesh

Heavy Metals

Heavy Metal ?10ppm

Arsenic ?3ppm

Lead ?3ppm

Mercury ?1ppm

Cadmium ?1ppm

Micro bacteria

Total plate count ?1000cfu/g

Yeast and Mould ?100cfu/g

Coli form Absent/g

Salmonella Absent/g



What Is HPMC E3

HPMC E3 refers to Hydroxypropyl Methylcellulose E3, which is a specific grade or type of hydroxypropyl methylcellulose. The E3 designation typically refers to the specific grade or specification of HPMC. These designations are used to differentiate various HPMC grades based on their physical and chemical properties, including factors like molecular weight, viscosity, and other characteristics.



Application of HPMC E3





KimaCell® HPMC E3 has become one of the most widely used pharmaceutical excipients at home and abroad, because HPMC has advantages that other excipients do not have.



Water solubility



Soluble in cold water below 40°C or 70% ethanol, basically insoluble in hot water above 60°C, but can gel.



Chemical inertness



HPMC is a kind of non-ionic cellulose ether. Its solution has no ionic charge and does not interact with metal salts or ionic organic compounds. Therefore, other excipients do not react with it during the preparation process.



Stability



It is relatively stable to acid and alkali, and can be stored for a long time between pH 3 and 11 without obvious change in viscosity. The aqueous solution of HPMC has anti-mildew effect and can maintain good viscosity stability during long-term storage. The quality stability of medicines using HPMC as preparation excipients is better than that of medicines using traditional excipients such as dextrin, starch, etc..



Adjustable viscosity



Different viscosity derivatives of HPMC can be mixed according to different ratios, and its viscosity can change according to certain rules, and has a good linear relationship, so it can be selected according to the demand. 2.5 Metabolism inert HPMC is not absorbed or metabolized in the body, and does not provide heat, so it is a safe pharmaceutical preparation excipient.



Security



HPMC is generally considered a non-toxic and non-irritating material.



Why Choose Kimacell HPMC E3

Kimcell is a reputable company known for its expertise in manufacturing and distributing a wide range of cellulose-based products, including Hydroxypropyl Cellulose E3, available for wholesale purchase. Kimcell stands out as a trusted source for Hydroxypropyl Cellulose E3 wholesale. Their products meet rigorous quality standards and are available in various grades and specifications, ensuring they can cater to the diverse requirements of their customers.



Kimcell can supply you with Hydroxypropyl Cellulose E3 in bulk, providing you with a dependable source of this essential ingredient. The company's unwavering commitment to product excellence, customer satisfaction, and competitive pricing makes them an ideal partner for businesses seeking reliable cellulose-based solutions.